Assays

B Cell Gene Rearrangement
IGH Somatic Hypermutation
Used to test chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) specimens.

IGH Gene Rearrangement Assays
Identifies IGH gene rearrangements using 3 master mixes that target the Framework 1-3 regions.

IGH Gene Clonality Assays
Developed by the BIOMED-2 Group, these assays identify IGH gene rearrangements using 3 master mixes that target the Framework 1-3 regions, and 2 master mixes that target the DH-JH rearrangements.

IGK Gene Clonality Assays
Developed by the BIOMED-2 Group, these assays identify IGK gene rearrangements using 2 master mixes that target the Vk 1-7 segments, the Kappa deletion element, and intron segment.

IGL Gene Clonality Assays
Developed by the BIOMED-2 Group, these assays identify gene rearrangements using 1 master mix that targets the Vl 1-3 segments.

T Cell Gene Rearrangement
TCRB Gene Clonality Assays
Developed by the BIOMED-2 Group, these assays identify gene rearrangements using 3 master mixes that target the Vb 1-24 and Db 1&2 gene segments.

TCRD Gene Clonality Assays
Developed by the BIOMED-2 Group, these assays identify gene rearrangements using 1 master mix that targets the Vd 1-6 and Dd 2&3 gene segments.

TCRG Gene Rearrangement Assay
Identifies gene rearrangements using 2 master mixes that target the Vg 1-9 gene semgments using two different sets of primer binding points.

TCRG Gene Clonality Assay
Developed by the BIOMED-2 Group, these assays identify gene rearrangements using 2 master mixes that target the Vg 1-11 gene segments. 

BCL1/JH Translocation Assays
Developed by the BIOMED-2 Group, these assays identify BCL1/JH t(11;14) translocations using 1 master mix that targets BCL1 MTC locus of chromosome 11 and the JH locus of chromosome 14.

BCL2/JH t(14;18) Translocation Assays
Identifies BCL2/JH t(14;18) translocations using 4 master mixes that target the Mbr and mcr loci on chromosome 18 and the JH locus of chromosome 14. This assay can be performed as a nested or non-nested assay.

BCL2/JH Translocation Assays
Developed by the BIOMED-2 Grouop, these assays identify BCL2/JH t(14;18) translocations using 3 master mixes that target the Mbr, 3' Mbr, and mcr loci on chromosome 18, and the JH locus of chromosome 14.

BCR/ABL t(9;22) Translocation Assays Identifies BCR/ABL t(9;22) translocations using 7 master mixes that target the p190 e1a2, p210 b3a2, and p210 b2a2 translocation products. This assay is a nested assay.

PML/RARa t(15;17) Translocation Assays
Identifies PML/RARa t(15;17) translocations using 3 master mixes that target both the short and long form translocation products. This assay is a nested assay.

Template Amplification Controls
Template amplification control master mixes are designed to test the quality and quantity of the DNA or RNA to be used in an assay.

B Cell Gene Rearrangement/Clonality Master Mixes
IGH Gene Rearrangement/Clonality Master Mixes
All IGH master mixes contained in both the IGH Gene Rearrangement Assays and the IGH Gene Clonality Assays.

IGK Gene Clonality Master Mixes
All IGK master mixes contained in the IGK Gene Clonality Assays.

IGL Gene Clonality Master Mixes
All IGL master mixes contained in the IGL Gene Clonality Assays.

T Cell Gene Rearrangement/Clonality Master Mixes
TCRB Gene Clonality Master Mixes
All TCRB master mixes contained in the TCRB Gene Clonality Assays.

TCRD Gene Clonality Master Mixes
All TCRD master mixes contained in the TCRD Gene Clonality Assays.

TCRG Gene Rearrangement/Clonality Master Mixes
All TCRG master mixes contained in both the T Cell Receptor Gamma Gene Rearrangement Assays, and the TCRG Gene Clonality Assays.

Translocation Master Mixes
BCL1/JH t(11;14) Translocation Master Mixes
All BCL1 master mixes contained in the BCL1/JH Translocation Assays.

BCL2/JH t(14;18) Translocation and BCL2/JH Translocation Master Mixes
All BCL2 master mixes contained in both the BCL2/JH t(14;18) Translocation Assays, and BCL2/JH Translocation Assays.

BCR/ABL t(9;22) Translocation Master Mixes
All BCR/ABL master mixes contained in the BCR/ABL t(9;22) Translocation Assays.

PML/RARa t(15;17) Translocation Master Mixes
All PML/RARa master mixes contained in the PML/RARa t(15;17) Translocation Assays. 

LymphoTrack™ IGH TrackOne (RUO)
LymphoTrack™ TrackOne Assays are used to identify tumor-specific clonal rearrangements and tumor-specific DNA sequence information for the design of tumor-specific primers and probe combinations used in our TrackTwo Assay Kits.

LymphoTrack™ IGH TrackTwo (RUO)

LymphoTrack™ TrackTwo Assays are used to:

• Monitor the effectiveness of anti-tumor agents
• Identify high risk and low risk tumors
• Detect and assess residual disease in samples
• Support research studies

Enzymes
PurePlus™ Reverse Transcriptase

PurePlus™ M-MLV Reverse transcriptase is highly robust and reliable product that outperforms other commercial enzymes, but is priced to yield substantial cost savings.

Buffers

PurePlus™ Reverse Transcriptase 10X Buffer

PurePlus™ MMLV RT 10X Buffer is designed to provide optimal performance with our MMLV Reverse Transcriptase enzymes.